Neuro-2a is a cell line that was taken from the brain tissue of a strain A albino mouse with neuroblastoma. The Neuro-2a cell line has a modal chromosome number of 95 and produces acetylcholinesterase and tubulin. Neuro-2a cells are susceptible to herpes simplex virus, vesicular stomatitis virus, and human poliovirus 1. Neuro-2a cells are neuroblasts that exhibit a neuronal and amoeboid stem cell mophology and adhere in culture in vitro, which makes them unique and reliable transfection hosts. A reagent to transfect Neuro-2a cells is available for purchase from Altogen Biosystems. This cell line can be used for the study of brain tumors as well as research in cell and molecular biology.
Brain tissue removed from an albino house mouse (Mus musculus) with neuroblastoma was first used to establish the Neuro-2a cell line. These cells exhibit amoeboid and neuronal stem cell morphology, they also produce a bountiful amount of microtubular protein within the body. This cell line is good as a transfection host, as it is susceptible to the human polio virus 1, vesicular stomatitis virus and the herpes simplex virus. Altogen Biosystems manufactures a transfection reagent for Neuro-2a that meticulously targets the neuroblastoma cells for further research of carcinogenic brain tumors. Transfection Reagent for Neuro-2a Cells (Neuroblastoma Cells, CCL-131)
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