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Neuro-2a Cell Line

Neuro-2a is a cell line that was taken from the brain tissue of a strain A albino mouse with neuroblastoma. The Neuro-2a cell line has a modal chromosome number of 95 and produces acetylcholinesterase and tubulin. Neuro-2a cells are susceptible to herpes simplex virus, vesicular stomatitis virus, and human poliovirus 1. Neuro-2a cells are neuroblasts that exhibit a neuronal and amoeboid stem cell mophology and adhere in culture in vitro , which makes them unique and reliable transfection hosts. A reagent to transfect Neuro-2a cells is available for purchase from Altogen Biosystems . This cell line can be used for the study of brain tumors as well as research in cell and molecular biology.
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Neuroblastoma Xenografts from Altogen

Altogen Biosystems is a recognized developer and laboratory for genetic research. Custom research offers and additional experiments include xenografts, toxicology assays, 28-day generation of stably-transfected cells, RNAi testing and more. Dedicated to assisting pharmaceutical companies with cutting-edge and specialized services, Altogen Biosystems endeavors to optimize modern laboratory discoveries. Visit Altogen’s catalog for brain cancer xenograft models and other tools for preclinical research and drug development.

Brain Cancer Research in Neuro-2a Cells

The Neuro-2a cell line was derived from the brain tissue of an albino mouse with a neuroblastoma. The cell line has been used extensively to study the formation of neuroblastomas and the resulting metastasis into bone tissues in children; the cell line is susceptible to viral infection and is consequentially an important model for investigating tumorigenesis in children after birth. With viruses such as poliovirus 1, vesicular stomatitis, and herpes simplex having the capability to be passed on to children during pregnancy, research with non-intrusive transfection reagents accompanying gene therapies can help elucidate cures to virus-caused cancers in children.

Neuro-2a Transfection Reagent (Neuroblastoma Cells, CCL131)

Brain tissue removed from an albino house mouse (Mus musculus) with neuroblastoma was first used to establish the Neuro-2a cell line. These cells exhibit amoeboid and neuronal stem cell morphology, they also produce a bountiful amount of microtubular protein within the body. This cell line is good as a transfection host, as it is susceptible to the human polio virus 1, vesicular stomatitis virus and the herpes simplex virus. Altogen Biosystems manufactures a transfection reagent for Neuro-2a that meticulously targets the neuroblastoma cells for further research of carcinogenic brain tumors.  Transfection Reagent for Neuro-2a Cells (Neuroblastoma Cells, CCL-131)