Brain tissue removed from an albino house mouse (Mus musculus) with neuroblastoma was first used to establish the Neuro-2a cell line. These cells exhibit amoeboid and neuronal stem cell morphology, they also produce a bountiful amount of microtubular protein within the body. This cell line is good as a transfection host, as it is susceptible to the human polio virus 1, vesicular stomatitis virus and the herpes simplex virus. Altogen Biosystems manufactures a transfection reagent for Neuro-2a that meticulously targets the neuroblastoma cells for further research of carcinogenic brain tumors.
Neuro-2a is a cell line that was taken from the brain tissue of a strain A albino mouse with neuroblastoma. The Neuro-2a cell line has a modal chromosome number of 95 and produces acetylcholinesterase and tubulin. Neuro-2a cells are susceptible to herpes simplex virus, vesicular stomatitis virus, and human poliovirus 1. Neuro-2a cells are neuroblasts that exhibit a neuronal and amoeboid stem cell mophology and adhere in culture in vitro , which makes them unique and reliable transfection hosts. A reagent to transfect Neuro-2a cells is available for purchase from Altogen Biosystems . This cell line can be used for the study of brain tumors as well as research in cell and molecular biology.